Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EEF2 All Species: 33.94
Human Site: S828 Identified Species: 57.44
UniProt: P13639 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13639 NP_001952.1 858 95338 S828 P G D P F D N S S R P S Q V V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001118006 1434 155458 S1404 P G D P F D N S S R P S Q V V
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P58252 858 95296 S828 P G D P F D N S S R P S Q V V
Rat Rattus norvegicus P05197 858 95265 S828 P G D P F D N S S R P S Q V V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515708 919 102141 T889 P G D P F D N T S R P C Q V V
Chicken Gallus gallus Q90705 858 95360 A828 P G D P F D S A S R P S Q V V
Frog Xenopus laevis NP_001080656 858 95409 T828 P G D P F D N T T R P S Q V V
Zebra Danio Brachydanio rerio XP_697966 861 95866 N831 P G D P Y D V N S K P S Q I V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13060 844 94440 S814 P G D P S E P S S K P Y A I V
Honey Bee Apis mellifera XP_392691 844 94564 N814 P G D P M E P N S R P Y Q V V
Nematode Worm Caenorhab. elegans P29691 852 94778 G822 P G D P L E A G T K P N Q I V
Sea Urchin Strong. purpuratus XP_001178871 842 94328 T812 G D D P I D P T T K S G I I V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32324 842 93271 T812 G S D P L D P T S K A G E I V
Red Bread Mold Neurospora crassa Q96X45 844 93243 T814 G G S P L D S T S K V G Q I V
Conservation
Percent
Protein Identity: 100 N.A. 59.7 N.A. N.A. 99 99.1 N.A. 92.3 97.3 95.2 92.4 N.A. 78.7 80.6 80.1 75.7
Protein Similarity: 100 N.A. 59.8 N.A. N.A. 99.5 99.6 N.A. 92.8 98.5 98.2 97.3 N.A. 86.9 87.7 88.6 85.9
P-Site Identity: 100 N.A. 100 N.A. N.A. 100 100 N.A. 86.6 86.6 86.6 66.6 N.A. 53.3 66.6 46.6 26.6
P-Site Similarity: 100 N.A. 100 N.A. N.A. 100 100 N.A. 93.3 100 100 93.3 N.A. 73.3 80 80 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 66.4 67.4
Protein Similarity: N.A. N.A. N.A. N.A. 78.7 80.8
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 40
P-Site Similarity: N.A. N.A. N.A. N.A. 60 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 8 0 0 8 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 8 93 0 0 79 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 22 0 0 0 0 0 0 8 0 0 % E
% Phe: 0 0 0 0 50 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 22 86 0 0 0 0 0 8 0 0 0 22 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 0 0 8 43 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 43 0 0 0 0 0 % K
% Leu: 0 0 0 0 22 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 43 15 0 0 0 8 0 0 0 % N
% Pro: 79 0 0 100 0 0 29 0 0 0 79 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 79 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 58 0 0 0 0 0 % R
% Ser: 0 8 8 0 8 0 15 36 79 0 8 50 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 36 22 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 8 0 0 0 8 0 0 58 100 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 15 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _